Emerging Essendon speedster Matt Guelfi will miss at least six weeks with a hamstring strain.
Guelfi, who finished third in the club's best and fairest last year, hurt himself at training late last week and on Tuesday he was diagnosed with a high-grade tear.
Guelfi had a strong pre-season until the first week of February.
A calf strain kept him out of action in Round 1, but the livewire returned to the senior team in Round 2 as the sub.
In the Bombers’ 28-point win over Gold Coast, he booted two goals.
It's understood his latest setback will see him miss at least six weeks, but potentially as many as two months.
In better news, fan favourite Anthony McDonald-Tipungwuti is back training fully this week after missing the last fortnight due to a quad issue.